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Primeva Labs
Triple Incretin Receptor Agonist

Retatrutide

LY3437943GGG Tri-AgonistReta

Retatrutide from Primeva Labs is offered strictly for research use only. Each order includes batch-specific CoA documentation, quality verification, and secure online ordering. Not for human or animal consumption.

Vial size20mg
Research Catalog Access
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CoA

What Is Retatrutide?

Research overview

Retatrutide (LY3437943) is an investigational triple-receptor agonist acting at the GIP, GLP-1, and glucagon receptors, studied in metabolic and body-weight research.

  • First triple agonist of the GIP, GLP-1, and glucagon receptors
  • Studied extensively in obesity and metabolic-dysfunction models
  • A major focus of current incretin-based metabolic research
  • Supplied strictly as a research-grade reference material

Research Applications

Studied in preclinical research models · not for human use

Body-weight research

Studied in models of energy balance, appetite, and adiposity.

Glycemic-control research

Examined for effects on glucose handling via incretin pathways.

Hepatic-fat models

Investigated in research on liver-fat and metabolic-dysfunction-associated steatosis.

Energy-expenditure studies

Explored for glucagon-receptor contributions to energy expenditure.

Proposed Mechanisms

Preclinical · proposed pathways

GLP-1 receptor agonism

Engages GLP-1 signaling associated with satiety and insulin secretion.

GIP receptor agonism

Adds GIP-receptor activity studied for complementary metabolic effects.

Glucagon receptor agonism

The third arm is studied for contributions to energy expenditure and lipid handling.

Combined incretin signaling

Tri-agonism is investigated for additive effects beyond single- or dual-agonists.

Mechanisms described above are drawn from preclinical (cell and animal) research and, where noted, early clinical literature. They are provided for educational context and should not be read as clinical or therapeutic claims.

Sources & References

Peer-reviewed research

Quality Verification cGLP · USP

Third-party tested by Analytical Formulations, Inc.
LATEST6-PANELSELECTED DOSAGE
99.57%
PURITY
Passed full 6-panel
View COA
VariantRetatrutide 10mg & 20mg (same batch)
Lot #1924414129
Labeled10mg
Actual10.18mg
TestedMay 2, 2026
FULL 6-PANEL6× tested
Qualitative IDLambda MaxMatches
Percent PurityCorr. Coeff.99.57%
Quantitative AssayBeer-Lambert10.18mg
Heavy MetalsTotal Quantity<20 ppb
TAMCAerobic Count0 CFU/g
TYMCYeast & Mold0 CFU/g
RP-HPLC · USP <1223> Sterility · LAL Endotoxin

Storage & Handling

Stability information
Protect from direct lightAvoid repeated freeze/thaw cyclesReconstitute before use
Lyophilized (powder)
-20°C · 24+ months
Reconstituted
2–8°C · ~30 days

Molecular Profile

Technical specifications
Vial Size20mg
ClassGLP-1 / GIP / Glucagon triple-receptor agonist
Molecular Weight~4731 g/mol
CAS Number2381089-83-2
FormatLyophilized peptide
Purity≥99% (HPLC)

Frequently Asked Questions

Retatrutide
Is Retatrutide for human use?
No. It is supplied strictly as a research-grade reference material for laboratory use, not for human or animal consumption.
What makes Retatrutide distinct?
It is the first compound studied as a simultaneous agonist of three receptors — GIP, GLP-1, and glucagon.
What purity is the material?
Each batch is independently tested and ships with a batch-specific Certificate of Analysis at greater than or equal to 99% purity by HPLC.
How is it stored?
Store lyophilized at -20°C; after reconstitution, refrigerate at 2-8°C and avoid repeated freeze-thaw cycles.

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