5-Amino-1MQ
5-Amino-1MQ from Primeva Labs is offered strictly for research use only. Each order includes batch-specific CoA documentation, quality verification, and secure online ordering. Not for human or animal consumption.
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What Is 5-Amino-1MQ?
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) studied for effects on cellular NAD+ and adipocyte metabolism.
- Membrane-permeable NNMT (nicotinamide N-methyltransferase) inhibitor
- Studied for raising intracellular NAD+ in adipocytes
- A focus of metabolic-flexibility and adiposity research
- Supplied strictly as a research-grade reference material
Research Applications
NAD+ metabolism research
Studied for preserving cellular NAD+ by inhibiting NNMT.
Adipocyte studies
Examined for altered adipose-tissue metabolism in preclinical models.
Body-weight research
Investigated for reduced fat mass and improved glucose tolerance in obese mice.
Metabolic-flexibility studies
Explored for links between NNMT activity and energy metabolism.
Proposed Mechanisms
NNMT inhibition
Inhibits NNMT, the enzyme that consumes nicotinamide and S-adenosylmethionine.
NAD+ preservation
Reduced nicotinamide methylation is studied for increased NAD+ salvage.
SIRT1 pathway
Higher NAD+ is investigated for downstream sirtuin (SIRT1) signaling.
Adipose remodeling
NNMT suppression is linked to altered adipocyte energy metabolism in models.
Mechanisms described above are drawn from preclinical (cell and animal) research and, where noted, early clinical literature. They are provided for educational context and should not be read as clinical or therapeutic claims.
Sources & References
Quality Verification cGLP · USP
Storage & Handling
Molecular Profile
Frequently Asked Questions
Is 5-Amino-1MQ for human use?
What is NNMT?
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