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Primeva Labs
Nootropic Research Peptide

Semax

SemaxACTH(4-10) analog

Semax from Primeva Labs is offered strictly for research use only. Each order includes batch-specific CoA documentation, quality verification, and secure online ordering. Not for human or animal consumption.

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CoA

What Is Semax?

Research overview

Semax is a synthetic peptide derived from a fragment of ACTH(4-10), developed in Russia and studied for neurotrophic (BDNF) and neuroprotective effects.

  • Synthetic ACTH(4-10) analog with a C-terminal Pro-Gly-Pro extension
  • Studied for BDNF upregulation and neuroplasticity
  • A focus of nootropic and neuroprotection research
  • Supplied strictly as a research-grade reference material

Research Applications

Studied in preclinical research models · not for human use

Neurotrophic research

Studied for upregulation of BDNF and nerve-growth-factor signaling.

Neuroprotection models

Examined for reduced infarct size in cerebral-ischemia research.

Cognition / learning studies

Investigated for effects on memory consolidation and attention in models.

Monoamine-signaling research

Explored for modulation of dopaminergic and serotonergic systems.

Proposed Mechanisms

Preclinical · proposed pathways

BDNF / TrkB pathway

Increases BDNF expression and downstream TrkB signaling in brain regions.

Neuroprotective signaling

Associated with anti-apoptotic and anti-inflammatory effects in ischemia models.

Monoaminergic modulation

Studied for effects on dopamine and serotonin turnover.

Metabolic stability

The Pro-Gly-Pro extension improves resistance to enzymatic breakdown.

Mechanisms described above are drawn from preclinical (cell and animal) research and, where noted, early clinical literature. They are provided for educational context and should not be read as clinical or therapeutic claims.

Sources & References

Peer-reviewed research

Quality Verification cGLP · USP

Third-party tested by Analytical Formulations, Inc.
LATEST6-PANELSELECTED DOSAGE
99.9%
PURITY
Passed full 6-panel
View COA
VariantSemax 10mg
Lot #
Labeled10mg
Actual10.35mg
TestedMar 21, 2026
FULL 6-PANEL6× tested
Qualitative IDLambda MaxConfirmed
Percent PurityCorr. Coeff.99.9%
Quantitative AssayBeer-Lambert10.35mg
Heavy MetalsTotal Quantity<20 ppb
TAMCAerobic Count0 CFU
TYMCYeast & Mold0 CFU
cGLP · USP Standards

Storage & Handling

Stability information
Protect from direct lightAvoid repeated freeze/thaw cyclesReconstitute before use
Lyophilized (powder)
-20°C · 24+ months
Reconstituted
2–8°C · ~30 days

Molecular Profile

Technical specifications
Vial Size10mg
SequenceMet-Glu-His-Phe-Pro-Gly-Pro
Molecular FormulaC37H51N9O10S
Molecular Weight813.92 g/mol
CAS Number80714-61-0
Purity≥99% (HPLC)

Frequently Asked Questions

Semax
Is Semax for human use?
No. It is supplied strictly as a research-grade reference material for laboratory use, not for human or animal consumption.
What is Semax derived from?
It is based on a fragment of ACTH(4-10) with a stabilizing extension, and is studied mainly for neurotrophic effects.
What purity is the material?
Each batch is independently tested and ships with a batch-specific Certificate of Analysis at greater than or equal to 99% purity by HPLC.
How is it stored?
Store lyophilized at -20°C; after reconstitution, refrigerate at 2-8°C and avoid repeated freeze-thaw cycles.

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