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Primeva Labs
NNMT Inhibitor Research Compound

5-Amino-1MQ

5-Amino-1MQ5-Amino-1-methylquinolinium

5-Amino-1MQ from Primeva Labs is offered strictly for research use only. Each order includes batch-specific CoA documentation, quality verification, and secure online ordering. Not for human or animal consumption.

Vial size50mg
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CoA

What Is 5-Amino-1MQ?

Research overview

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) studied for effects on cellular NAD+ and adipocyte metabolism.

  • Membrane-permeable NNMT (nicotinamide N-methyltransferase) inhibitor
  • Studied for raising intracellular NAD+ in adipocytes
  • A focus of metabolic-flexibility and adiposity research
  • Supplied strictly as a research-grade reference material

Research Applications

Studied in preclinical research models · not for human use

NAD+ metabolism research

Studied for preserving cellular NAD+ by inhibiting NNMT.

Adipocyte studies

Examined for altered adipose-tissue metabolism in preclinical models.

Body-weight research

Investigated for reduced fat mass and improved glucose tolerance in obese mice.

Metabolic-flexibility studies

Explored for links between NNMT activity and energy metabolism.

Proposed Mechanisms

Preclinical · proposed pathways

NNMT inhibition

Inhibits NNMT, the enzyme that consumes nicotinamide and S-adenosylmethionine.

NAD+ preservation

Reduced nicotinamide methylation is studied for increased NAD+ salvage.

SIRT1 pathway

Higher NAD+ is investigated for downstream sirtuin (SIRT1) signaling.

Adipose remodeling

NNMT suppression is linked to altered adipocyte energy metabolism in models.

Mechanisms described above are drawn from preclinical (cell and animal) research and, where noted, early clinical literature. They are provided for educational context and should not be read as clinical or therapeutic claims.

Sources & References

Peer-reviewed research

Quality Verification cGLP · USP

Third-party tested by Analytical Formulations, Inc.
LATEST6-PANELSELECTED DOSAGE
98.7%
PURITY
Passed full 6-panel
View COA
Variant5-Amino-1MQ 50mg
Lot #
Labeled50mg
Actual54.21mg
TestedDec 28, 2025
FULL 6-PANEL6× tested
Qualitative IDLambda MaxConfirmed
Percent PurityCorr. Coeff.98.7%
Quantitative AssayBeer-Lambert54.21mg
Heavy MetalsTotal Quantity<10 ppb
TAMCAerobic Count0 CFU
TYMCYeast & Mold0 CFU
cGLP · USP Standards

Storage & Handling

Stability information
Protect from direct lightAvoid repeated freeze/thaw cyclesReconstitute before use
Lyophilized (powder)
-20°C · 24+ months
Reconstituted
2–8°C · ~30 days

Molecular Profile

Technical specifications
Available Sizes5mg, 50mg
ClassNNMT inhibitor (small molecule)
Chemical Name5-amino-1-methylquinolinium
Molecular FormulaC10H11N2⁺ (cation)
Molecular Weight~159.2 g/mol (cation)
Purity≥99% (HPLC)

Frequently Asked Questions

5-Amino-1MQ
Is 5-Amino-1MQ for human use?
No. It is supplied strictly as a research-grade reference material for laboratory use, not for human or animal consumption.
What is NNMT?
Nicotinamide N-methyltransferase is an enzyme studied for its role in NAD+ metabolism and adipose-tissue energy handling.
What purity is the material?
Each batch is independently tested and ships with a batch-specific Certificate of Analysis at greater than or equal to 99% purity by HPLC.
How is it stored?
Store the lyophilized or solid material as labeled; once in solution, refrigerate at 2-8°C and avoid repeated freeze-thaw cycles.

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